Home > AZD0284

molecules of the month

<< Back to August

AZD0284

Recent Publication

oral RORC2 inverse agonist for psoriasis

100 mg PO BID, Ph. I term. due to preclin. Data

from opt. of lit. inverse agonist

Journal of Medicinal Chemistry

AstraZeneca, Gothenburg, Sweden

The AstraZeneca oral RORgt inverse agonist, AZD0284, is an inverse agonist of the nuclear receptor RORC2 (RORγt). Reviewer Chris Gampe says, “targeting the activation and function of Th17 cells has been successful…

this content is exclusive to
Premium members

Unlock this content with a Premium membership to read it now.

LEARN MORE

AZD0284

this content is exclusive to Premium members

this content is exclusive to
Premium members