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CXCR7 GPCR insurmountable antagonist
target engagement in rodent, 61% F in dog
from 300k HTS vs. _-arrestin recruitment, opt.
J. Med. Chem., Dec. 14, 2020
Idorsia Pharma (Actelion), Allschwil, CH
Idorsia/Actelion CXCR7 GPCR insurmountable antagonist
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