Drug Hunter Categories and List of Cheat Sheets

List of Content Categories | List of Cheat Sheets

Drug Hunter original content generally falls into a few categories, summarized below. A list of cheat sheets is also summarized below and on the resources page for ease of navigation.

List of Content Categories

Cheat Sheetshttps://drughunter.com/category/cheatsheets/#Contain page-sized graphics with information (e.g. Approved Covalent DrugsLogD Cheat SheetTopliss SchemePK Cheat Sheet)
Case Studieshttps://drughunter.com/category/case-studies/#Discussions of specific drug discovery programs or drug syntheses (e.g. VoxelotorPembrolizumabImatinib)
Articleshttps://drughunter.com/category/articles/#Discussions of specific topics related to drug discovery topics (e.g. Chimeric DegradersLead-Finding)
Companieshttps://drughunter.com/category/drugdiscoverycompanies/#Highlights or summaries of drug discovery companies (e.g. 2019 Small Molecule and Biologic Biotech IPOs)
Highlightshttps://drughunter.com/category/highlights/#Highlights of scientific advances in the industry (e.g. Small Molecules of the Month2019 Biologic Drug Approvals)
Fundamentalshttps://drughunter.com/category/fundamentals/#Discussions of fundamental concepts related to drug discovery (e.g. Square-Cube LawWhy LogD MattersTopliss Cheat SheetsWhat is a Biologic Drug?)
Perspectiveshttps://drughunter.com/category/perspectives/#Discussions of drug discovery industry practices (e.g. Don’t Work on Things That Don’t Work)
Chemistryhttps://drughunter.com/category/chemistry/#Topics tailored to a chemistry audience (e.g. Pd-Couplings Cheat SheetAdventures in Atropisomerism)

Back to top

List of Cheat Sheets

LogD Cheat Sheethttps://drughunter.com/logdsheet/#Summary of expected LogD and potency shifts expected from common functional group additions
PK Cheat Sheethttps://drughunter.com/pk-cheat-sheet/#Summary of important parameters when considering in vivo studies
Topliss Schemehttps://drughunter.com/topliss/#Graphical summary of the Topliss design scheme
Approved Covalent Drug Mechanismshttps://drughunter.com/covalents1/#Summary of mechanisms of approved covalent drugs
Pd-Couplings Cheat Sheethttps://drughunter.com/pd-couplings-cheat-sheet/#Summary of common Pd-coupling conditions to try first
Unusual Molecular Interactionshttps://drughunter.com/pdbgems/#Summary of unusual molecular interactions detected in X-ray co-crystal structures of inhibitors
Bioactivation of Structural Alertshttps://drughunter.com/bioactivation-of-structural-alerts/#Summary of mechanisms of bioactivation of common structural alerts
Managing DILI Riskhttps://drughunter.com/dilirisk/#Summary of assays and strategies used to mitigate idiosyncratic liver toxicity
Kinase Inhibitor Classeshttps://drughunter.com/kinase-inhibitor-types-predicted-with-machine-learning/#Summary of binding modes of Type I-II kinase inhibitors
2019 Small Molecule Approvalshttps://drughunter.com/2019newdrugs/#Summary of 2019 approved small molecule drugs
2019 Biologic Drug Approvalshttps://drughunter.com/2019biologics/#Summary of 2019 approved biologics

Drug Hunter is always under construction. If you have any feedback on how to make the site more useful or easier to navigate, please let us know by reaching out to [email protected]

Back to top