Synthetic Access to Stable Atropisomers in Drug Discovery via Catalysis
Drug candidates exhibiting atropisomerism are often considered challenging for development by pharmaceutical professionals from synthetic and regulatory perspectives. Molecules that exist as stable atropisomers can be acceptable for development, but are often difficult to synthesize in their isomerically pure form. Modern catalysis, chromatographic separation, and crystallographic resolution methods have made atropisomeric drugs more accessible on…
Drug Discovery Technology Review: Emerging Tools and Modalities in 2022Q2/Q3
We did a deep dive into the pharmaceutical industry’s 2022Q2/Q3 news, and there’s a ton of exciting updates to share. In this review, we highlight some emerging companies, technologies, and drug discovery modalities we thought drug hunters would find interesting, including: New strategies for covalent protein modification Different methods for screening drug candidates and targets…
Small Molecule and Biotechnology-Based Therapeutics for Immunology: 2021 IPO Review Pt. VI
This article is Part VI of a review series covering all the initial public offerings for the biotech and pharmaceutical industries in 2021. Pt. I and Pt. II provided an overview of 2021 IPOs by therapy area, technology, and therapeutic class. Pt. III and Pt. IV provided a deep dive into the 2021 IPOs for…
Small Molecule and Biotechnology-Based Therapeutics for Neurology-Focused Companies: 2021’s IPOs Part V
This article is Part 5 of a review series covering all the initial public offerings for the biotech and pharmaceutical industries in 2021. Part 1 and Part 2 provided an overview of 2021 IPOs by therapy area, technology, and therapeutic class. Part 3 and Part 4 provided a deep dive into the 2021 IPOs for…
Biotechnology-Based Molecules in Oncology: 2021 IPO Review Pt. IV
This short article and poster summary takes a deeper look into the 2021 IPOs for biotechnology-based therapeutics being developed by oncology-focused companies, including: Antibody-drug conjugates Monoclonal antibodies Protein-based therapeutics Cell and gene therapies Other biotechnology-based therapeutics This article is Part 4 of a review series covering all of the initial public offerings for the biotech…
Small Molecules in Oncology from Emerging Companies: 2021’s IPOs Pt. III
This article is Part 3 of a review series covering all of the initial public offerings for the biotech and pharmaceutical industries in 2021. Part 1 provided an overview of 2021 IPOs by therapy area, technology, and therapeutic class. Part 2 provided an overview of 2021 IPOs by therapeutic area. This short article takes a…