This section contains case studies, industry highlights, minireviews, and other articles for drug discovery professionals. Check out the resources page for posters, educational content, lists of drug approvals, and more.
“compound 2” is a heme-displacing IDO1 inhibitor with a similar binding mode to BMS-986205 with a low projected human dose. A…
molecule
2 years ago ●
1 min read
“Compound 10” is a potent and selective inhibitor of Class I histone deacetylases (HDAC1/2/3) which increases HIV activity in treatment-suppressed patient…
molecule
2 years ago ●
1 min read
AB680 is a potent (5 pM) and selective inhibitor of CD73, a nucleotidase that metabolizes AMP to immunosuppressive extracellular adenosine. AB680…
molecule
2 years ago ●
1 min read
BAY 1895344 is a potent and highly selective inhibitor of the ATR kinase, which is involved in the DNA damage response.…
molecule
2 years ago ●
1 min read
“compound 18” is an oral inducer of fetal hemoglobin (HbF) intended to treat anemias such as sickle cell disease and beta-thalassemia.…
molecule
2 years ago ●
1 min read
JNJ-53718678 is a potent and orally available fusion inhibitor of the RSV virus, optimized from a prior oral inhibitor, BMS-433771. The…
molecule
2 years ago ●
1 min read
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