This section contains case studies, industry highlights, minireviews, and other articles for drug discovery professionals. Check out the resources page for posters, educational content, lists of drug approvals, and more.
The Galapagos-Servier selective ADAMTS-5 metalloproteinase inhibitor (GLPG1972) recently completed a Ph. II study for knee osteoarthritis. Identification of small molecule…
molecule
2 years ago ●
1 min read
The Bristol Myers Squibb apelin receptor (APJ) GPCR agonist (“compound 14”) is a clinical candidate for heart failure which completed…
molecule
2 years ago ●
1 min read
The Athenex/Hanmi Pharmaceutical P‑gp transporter inhibitor (encequidar) is a gut-restricted compound intended to reduce efflux and increase absorption of the…
molecule
2 years ago ●
1 min read
The Servier thrombin activatable fibrinolysis inhibitor (TAFIa) inhibitor (S62798) is a fibrinolytic (clot degrading) agent which entered Ph. II in the…
molecule
2 years ago ●
1 min read
The Cerevance/Takeda GPR6 inverse agonist (CVN424) is an oral, once-daily clinical candidate in Ph. II for Parkinson’s disease after completing…
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2 years ago ●
1 min read
The AbbVie BCL-2 inhibitor prodrug (ABBV-167) is a phosphate prodrug of venetoclax used for treatment of chronic lymphocytic leukemia (CLL).…
molecule
2 years ago ●
1 min read
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