This section contains case studies, industry highlights, minireviews, and other articles for drug discovery professionals. Check out the resources page for posters, educational content, lists of drug approvals, and more.
Retinol-binding protein 4 (RBP4) is the sole carrier for retinol (vitamin A). It may also play a role in diabetes…
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2 years ago ●
1 min read
RP-3500 is an oral ATR kinase inhibitor and Ph. II clinical candidate for advanced solid tumors with ATRi-sensitizing mutations, alone…
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2 years ago ●
1 min read
Gout is caused by the buildup of uric acid. The main treatments are drugs that increase uric acid secretion (uricosurics,…
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2 years ago ●
2 mins read
JAK kinases are now well-established targets in immunology, but the class has always had safety concerns hanging over it. The…
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2 years ago ●
2 mins read
Kinase inhibitors are increasingly being explored for diseases beyond cancer. While SGK1 has been a cancer target, SGK1 has also…
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2 years ago ●
1 min read
Vanin-1 is a biotinidase (nitrilase superfamily) that hydrolyzes pantetheine. Despite the critical role of pantetheine, vanin-1 deficient mice don’t appear…
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2 years ago ●
2 mins read
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