This section contains case studies, industry highlights, minireviews, and other articles for drug discovery professionals. Check out the resources page for posters, educational content, lists of drug approvals, and more.
MIW815 (ADU-S100) is a first-in-class STING agonist for cancer immunotherapy. Agonism of the STING (stimulator of IFN genes) receptor, true…
molecule
2 years ago ●
2 mins read
MRTX1719 is PRMT5-MTA complex inhibitor for the treatment of MTAP-deleted cancers currently in IND-enabling studies. PRMT5 is a target of…
molecule
2 years ago ●
2 mins read
Compound 15 is a gut-restricted inhibitor of NaPi2b, a sodium-dependent phosphate transport protein in the solute carrier (SLC) family. NaPi2b…
molecule
2 years ago ●
1 min read
DS-3801b is a non-macrolide GPR38 agonist and a Ph. I clinical candidate for treatment of chronic constipation (SAD 1-100 mg…
molecule
2 years ago ●
1 min read
LEO 134310 is a non-steroidal, selective glucocorticoid receptor (GR) agonist in Ph. I for plaque psoriasis. Glucocorticoid receptor modulators are…
molecule
2 years ago ●
2 mins read
bradanicline (ATA-101 or TC-5619) is a molecule first disclosed a decade ago by Targacept. It is a selective agonist of…
molecule
2 years ago ●
1 min read
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