This section contains case studies, industry highlights, minireviews, and other articles for drug discovery professionals. Check out the resources page for posters, educational content, lists of drug approvals, and more.
By Michael Lambrecht We all knew process scientists were good, but the Merck and Codexis teams just took it to…
Article
4 years ago ●
5 mins read
Context. GNE-064 (Genentech) is an oral inhibitor of the bromodomains of SMARCA2/4 and PBRM1 being developed as a tool compound.…
molecule
12 months ago ●
4 mins read
Having a clinical drug-induced liver injury (DILI) signal is a surefire way to kill a drug candidate in non-serious indications…
Article
4 years ago ●
6 mins read
Context. “Compound 33” (Merck) is a cGMP-dependent protein kinase G1α (PKG1α) activator cGMP modulation is considered one of the most…
molecule
1 year ago ●
5 mins read
The C-H --- O hydrogen bond is so well established in structural biology today, that it's been overlooked that the…
Article
4 years ago ●
4 mins read
Context. RP-6306 is an oral protein kinase, membrane-associated tyrosine/threonine 1 (PKMYT1) Inhibitor being developed for various solid tumors. PKMYT1, together…
molecule
1 year ago ●
5 mins read
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