This section contains case studies, industry highlights, minireviews, and other articles for drug discovery professionals. Check out the resources page for posters, educational content, lists of drug approvals, and more.
Context. Sudapyridine (WuXi AppTec) is an oral mycobacterial ATP synthase inhibitor being developed for tuberculosis (TB). Despite the significant success…
molecule
10 months ago ●
4 mins read
Checkpoint inhibitors like pembrolizumab (Keytruda) have revolutionized treatment for many late-stage cancer patients, including Jimmy Carter. Recently, Keytruda stunned the…
Article
5 years ago ●
10 mins read
Context. Dorzagliatin (Hua Medicine) is an oral dual-acting full glucokinase (GK) activator being developed for type 2 diabetes. More than…
molecule
10 months ago ●
5 mins read
Knochel's group has shown that you can fluorinate Grignard reagents without decomposition via single-electron transfer reactivity (SET) by a simple…
Article
5 years ago ●
3 mins read
Context. JDQ443 (Novartis Institute for Biomedical Research) is an oral KRASG12C inhibitor being developed for various advanced solid tumors. Despite…
molecule
11 months ago ●
6 mins read
Gleevec (imatinib) was the first tyrosine kinase inhibitor approved for the treatment of cancer and one of the first products…
Article
5 years ago ●
10 mins read
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