This section contains case studies, industry highlights, minireviews, and other articles for drug discovery professionals. Check out the resources page for posters, educational content, lists of drug approvals, and more.
Context. JNJ-64264681 (Janssen) is a covalent Bruton’s tyrosine kinase (BTK) inhibitor being developed for hematological malignancies. The first-in-class irreversible BTKi…
molecule
4 months ago ●
4 mins read
Thank you to all of the drug hunters who attended our second drug discovery webinar! You can find the video…
Article
10 months ago ●
1 min read
Context. BI-0474 (Boehringer Ingelheim) is a covalent KRASG12C inhibitor. KRAS continues to be a hotly pursued oncotarget since the first…
molecule
4 months ago ●
5 mins read
The FDA in 2021 approved four novel small molecule drugs for various infectious diseases, including human immunodeficiency virus type-1 (HIV-1),…
Article
10 months ago ●
12 mins read
Context. “Compound 57” (Roche) is an oral allosteric EGFRL858R inhibitor being developed for NSCLC. Drug resistance and associated disease relapse…
molecule
4 months ago ●
5 mins read
In this highlight, Dr. Dennis C. Koester reviews treatment options for HIV and explains how small molecule long-acting injectables (LAIs)…
Article
11 months ago ●
7 mins read
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