This section contains case studies, industry highlights, minireviews, and other articles for drug discovery professionals. Check out the resources page for posters, educational content, lists of drug approvals, and more.
Target-driven drug discovery evolves over time and is influenced by understanding of disease biology, technical innovation, and most of all,…
Article
9 months ago ●
13 mins read
What is it? Emraclidine (CVL-231) is a selective positive allosteric modulator (PAM) of the cholinergic M4 muscarinic receptor (GCPR) and…
molecule
2 months ago ●
5 mins read
In June 2022, the FDA approved vutrisiran (Amvuttra), a small interfering RNA (siRNA) for polyneuropathy of hereditary transthyretin-mediated (ATTR) amyloidosis…
Article
9 months ago ●
6 mins read
What is it? “Compound 25” is a selective, CNS-penetrant, ATP-competitive LRRK2 inhibitor that entered preclinical candidate enabling studies but was…
molecule
2 months ago ●
4 mins read
In the early 90’s, Wayne (Haifeng) Tang and Ray Zhao formed a friendship in high school in China. They were…
Article
9 months ago ●
2 mins read
What is it? Compound 49 is an orally available CD73 inhibitor with dose-dependent PK/PD and an immune-mediated antitumor mechanism of…
molecule
2 months ago ●
3 mins read
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