This section contains case studies, industry highlights, minireviews, and other articles for drug discovery professionals. Check out the resources page for posters, educational content, lists of drug approvals, and more.
A protein degradation approach to overcome paradoxical RAF activation. CFT1946 from C4 Therapeutics is a potent, selective, and orally bioavailable…
molecule
3 months ago ●
6 mins read
At AAPS 2022, I hosted a symposium where Ovoca Bio plc's Head of Research, Mikhail Lomonosov told us about orenetide.…
Article
11 months ago ●
3 mins read
A P2X3-selective antagonist for chronic cough without taste effects. Camlipixant is an orally administered antagonist of the ATP-sensing P2X3 homotrimeric…
molecule
4 months ago ●
8 mins read
Drug candidates exhibiting atropisomerism are often considered challenging for development by pharmaceutical professionals from synthetic and regulatory perspectives. Molecules that…
Article
11 months ago ●
5 mins read
And now for something completely different. The recent approvals of Ras(off)-targeting KRASG12C inhibitors sotorasib and adagrasib, decades in the making,…
molecule
4 months ago ●
7 mins read
No time to research ideas before your next team meeting? Grab a coffee and check out these key molecules. Click…
Article
11 months ago ●
1 min read
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