This section contains case studies, industry highlights, minireviews, and other articles for drug discovery professionals. Check out the resources page for posters, educational content, lists of drug approvals, and more.
The first non-ATP-competitive inhibitor of the long-pursued PI3Kδ kinase. Phosphatidylinositol-3-kinase (PI3K) has received intense attention as a drug target from…
molecule
4 months ago ●
8 mins read
PI3 kinases are part of the PI3K/Akt/mTOR signaling pathway that is downstream of Receptor Tyrosine Kinases (RTKs), G-protein-coupled receptors (GPCR),…
Article
11 months ago ●
11 mins read
A potential first-in-class oral antibiotic with recent positive Ph. III data. The orally administered gepotidacin is a member of a…
molecule
4 months ago ●
5 mins read
Despite significant investment over the past decade, only a handful of companies are now bringing clinical candidates discovered with the…
Article
11 months ago ●
10 mins read
A second-generation AR bifunctional degrader for drug-resistant prostate cancer. ARV-766 is Arvinas’ second bifunctional CRL4CRBN E3 ligase-based androgen receptor (AR)…
molecule
4 months ago ●
6 mins read
There have been numerous reviews on the impact of AI/ML in drug discovery looking at broad numbers, but with the…
Article
11 months ago ●
12 mins read
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