This section contains case studies, industry highlights, minireviews, and other articles for drug discovery professionals. Check out the resources page for posters, educational content, lists of drug approvals, and more.
“Compound (P)-14″ is a PI3K beta-isoform selective lipid kinase inhibitor. While the compound is potent and has excellent oral PK in…
molecule
2 years ago ●
1 min read
FT385 is a covalent inhibitor of the USP30 deubiquitinating enzyme with a cyanopyrrolidine warhead. Identifying selective active-site inhibitors of de-ubiquitinating enzymes…
molecule
2 years ago ●
1 min read
CC-92480 (Celgene/Bristol Myers Squibb (BMS) oral in vivo CRBN-based selective IKZF1/3 degrader)
molecule
2 years ago ●
1 min read
“PROTAC 6” (GlaxoSmithKline (GSK) IAP-based selective RIPK2 degrader with prolonged in vivo PD)
molecule
2 years ago ●
1 min read
GSK620 (GlaxoSmithKline (GSK) oral in vivo BD2 domain selective BET inhibitor)
molecule
2 years ago ●
1 min read
Merck hArg1 inhibitor (Merck oral in vivo human arginase 1 inhibitor) DHMOTM2020-03-04
molecule
2 years ago ●
1 min read
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