Here is a visual summary of the small molecules with their mechanism of action, indication, and dosing regimen listed.3 Happy new year, and looking forward to a great 2020! You can find a higher resolution PDF at the bottom of the page.
2019 Small Molecule Drug Approvals PDF Download:
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- Including istradefylline which was first approved in Japan, but not including brilliant blue G, fluorodopa F18, Ga-68-DOTATOC, bremelanotide, afamelanotide, and ferric maltol, which could all be considered small molecules by some definitions: https://www.fda.gov/drugs/new-drugs-fda-cders-new-molecular-entities-and-new-therapeutic-biological-products/novel-drug-approvals-2019
- The ADC approvals include the anti-CD79b agent polatuzumab vedotin (Polivy), the anti-nectin-4 agent enfortumab vedotin (Padcev), and the anti-HER2 agent fam-trastuzumab deruxtecan (Enhertu), all for oncology.
- From respective FDA drug labels.